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NIH Asks Judge to Suspend Stem Cell Research Injunction

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first_imgWarning of a “devastating impact” on ongoing research, government lawyers this afternoon asked a federal court to stay a preliminary injunction that last week forced the National Institutes of Health (NIH) to suspend future grant payments to study human embryonic stem cells (hESC) and shut down its in-house research on hESCs. The Department of Justice (DOJ) filed a 23-page memorandum in support of an emergency motion to stay the injunction pending an appeal with the United States District Court for the District of Columbia, whose chief judge, Royce Lamberth, issued the stunning 23 August ruling. DOJ argues that the injunction should be stayed “to avoid terminating research projects midstream, invalidating results in process, and impeding or negating years of scientific progress toward finding new treatments” for diseases such as diabetes and spinal cord injuries. The motion calls the judge’s order to stop funds “sweeping,” noting it covers research that began in 2002 during the Bush Administration. DOJ says this is “causing irrevocable harm” to millions of patients who could benefit from hESC research, NIH, hundreds of scientists, and taxpayers who have spent hundreds of millions of dollars on hESC research. It is already having “disastrous consequences” for $9.5 million in NIH intramural research on hESCs, which the agency began shutting down yesterday, DOJ states. Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)The brief discusses DOJ’s disagreement with Judge Lamberth’s view that NIH’s 2009 guidelines allowing work on hESCs violates the Dickey-Wicker amendment, a 14-year-old law barring the use of federal funds on research that involves the destruction of embryos. The brief also take issue with the arguments of the two plaintiffs—researchers James Sherley and Theresa Deisher. They claim that they are harmed by the NIH policy because allowing research on hESCs has decreased their chances of winning funding to study adult stem cells. The DOJ brief notes that applications using hESCs and adult cells “are not in direct competition,” that Sherley received funding from NIH after the guidelines came out, and that Deisher apparently has never even applied for NIH funding. NIH Director Francis Collins wrote a 12-page affidavit in support of the DOJ motion. It describes four specific projects that will run out of funds in September—including work at Children’s Hospital in Boston comparing hESCs to induced pluripotent stem cells. Since 2001, the affidavit says, NIH has spent more than $546 million on hESC research. The injunction “will have extraordinary adverse effects” on the development of new therapies and work on hESCs “could be lost irretrievably or could take years to recreate,” Collins attests. Legal experts have told ScienceInsider that they expect Lamberth to deny the request for a stay. The DOJ brief says that if the District Court hasn’t ruled by next Tuesday, 7 September, the government will take its request to the U.S. Court of Appeals the next day. Another document notifies the District Court that DOJ plans to appeal the preliminary injunction to the Appeals Court. See our complete coverage of this issue.last_img read more

Misleading sugar structures produce bitter result for protein sleuths

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first_imgStructure determines function. It’s the canon among biologists who seek to understand a protein’s role in the body by mapping the positions of its atoms and so deducing the molecule’s three-dimensional shape. But many proteins come coated with sugar chains that alter their structures, influencing the way they interact with one another, bind to receptors, and even act as medicines. Now, a new analysis offers the disturbing suggestion that most of the publicly deposited structures of these sugar appendages are wrong. The inaccuracies not only clog up databases of protein maps, but also misinform biologists and drug designers, who use the structural information to design novel molecular therapies.The notion that sugar structures are difficult to pin down isn’t new, says Carolyn Bertozzi, a glycobiologist at Stanford University in Palo Alto, California, who was not involved in the study. Sugar molecules’ small size and flexibility can make it hard to identify their exact conformation. Still, the new work quantifies the scale of the problem and so “delivers an important message,” Bertozzi says. The incorrect structures, she adds, “reveal widespread ignorance of chemistry and glycobiology, or at least profound inattention to the [sugar] component” of protein structure.Structural biologists determine the shapes of proteins and their attached sugars primarily with x-ray crystallography. The technique bombards crystals containing a vast number of identical proteins with short bursts of x-rays, and then tracks how those x-rays ricochet off. Different atoms cause x-rays to recoil in distinct ways. By charting the ricochet patterns, researchers can work out the most likely configuration of a protein. Still, x-ray data always have some blur to them, which makes it challenging to assign the exact position of all the atoms.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Structural biologists sharpen their images with computer modeling software that constrains where specific atoms can be positioned, based on well-understood factors such as the length of the bonds between atoms and the angles of those bonds. “This has been highly successful for the protein and, more recently, the nucleic acid components of crystal structures,” says Kevin Cowtan, a structural biologist at the University of York in the United Kingdom. However, “some of those restraints are missing or wrong for sugars, and thus many [sugar structures] have been built in unrealistic forms,” says Jon Agirre, Cowtan’s structural biology colleague at York.Cowtan, Agirre, and their York colleagues report online this month in Nature Chemical Biology that this problem is widespread. The researchers examined the structures of the nearly 50,000 biologically relevant sugars in two major databases of protein structures, the Protein Data Bank (PDB) and PDB_REDO. Using a sugar-specialized structure modeling program developed by Agirre, they analyzed the raw x-ray data of each sugar deposited in the database to determine its expected shape and checked how well it matched the structure reported. They scored each result between 0 and 1 to reflect how well the results matched, a measure they refer to as a density correlation. According to Cowtan, above 0.9 indicates a very good fit, and confidence in the match drops off rapidly below that.For their paper, the York researchers focused their analysis on one subgroup of sugars—called N-glycan-forming D-pyranosides—which are known to adopt a handful of specific and energetically favorable conformations, such as an upward- or downward-facing bowl. On the plus side, the York researchers found that 7.8% of the subgroup’s structures have good fits. The bad news: Sixty-four percent had a correlation to density of less than 0.8, reflecting what Agirre calls “a poor fit to the experimental data.” And there was worse news: “Twenty-five percent of the studied sugars are [reported to be] in energetically improbable conformations; these are most certainly wrong,” Agirre concludes.He and his co-authors note that in the 1980s, the structural biology community faced a similar problem of prevalent mistakes in the positioning of atoms in amino acids and those amino acids in proteins. But the community solved it by coming together to improve their refinement software and developing a community-wide standard of computing structure positions. That hasn’t happened yet with sugars, Cowtan says. But the crucial role many sugars play in cellular communication and function is becoming clearer. So, he concludes, “the whole structural biology community should be worried about getting these correct.”last_img read more

Indian archers get 3 years suspension for missing medal match

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first_imgThree junior archers and coach have been suspended by The Association of Indian Universities (AIU) for three years after being found guilty of missing their bronze medal play-off match against Italy during the World University Games in South Korea.The suspended archers of men’s compound team Gurwinder Singh, Kanwalpreet Singh, and Aman along with their coach Jiwanjot Singh have been banned from participating in inter-university or international university games for a period of three years.The AIU has also asked the suspended archers and their coach to refund the amount of expenses that was incurred for their equipment, training, kit and travel.It was reported that the archers missed their crucial bronze medal play-off match because they were all off for sighseeing. However, that time the coach Jiwanjot had rubbished the reports and blamed it on equipment malfunction.last_img read more

Domestic workers to be brought under ESI fold soon: Dattatreya

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first_imgHyderabad, Aug 14 (PTI) Labour Ministry will soon launch a social security scheme for domestic workers on pilot basis in Delhi and Hyderabad as part of Central governments commitment to provide health insurance for all, Union Minister Bandaru Dattatreya said today.”We will roll out a new scheme to bring domestic workers under the ESI fold. This scheme intends to provide ESI facilities to domestic workers. Employers need to contribute Rs 200 monthly towards this scheme that will enable medical facilities for domestic workers,” Dattatreya told reporters here.”We have decided to start the scheme soon as pilot project in Delhi and Hyderabad … we will involve NGOs also besides will talk to state governments to make the scheme better,” the Union Minister of State for Labour and Employment said, adding that Rs 200 per month contribution by employers will provide medical insurance for domestic workers and his/her family.Reiterating governments commitment to bring all the unorganised sector workers under social security schemes, he said the process has begun to include around five crore construction workers to provide them with EPF and ESI facilities.On Rajya Sabha recently passing the Maternity Benefit (Amendment) Bill 2016, that provides for 26 weeks maternity leave, Dattatreya said India will move to third position in terms of the number of weeks for maternity leave after Norway and Canada.”The Bill will benefit over 1.8 million women workers,” he mentioned.The minister said Child Labour (Prohibition and Regulation) Amendment Bill-2012 has been passed by both Lok Sabha and Rajya Sabha, besides Employees Compensation (Amendment) Bill-2016 and Factories (Amendment) Bill-2016 have also been passed by Lok Sabha.advertisementReacting to a query on enforcing the rules of various labour laws, Dattatreya said, “We are trying to constitute dedicated teams giving them provisions to act ensuring effective enforcement (monitoring of rules).”Six regional conferences will be held across the country by the Labour Ministry in this regard, he added. PTI VVK GK IKAlast_img read more

The perfect Father’s Day gift: The Dad Box by Ernest Alexander

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first_img How to Cure Prosciutto at Home Editors’ Recommendations It’s Time to Ditch Your Sleeping Bag for a Versatile, Lightweight Camping Quilt The Mission Workshop Khyte Sets a New Standard for Messenger Bags Did you get your dad something special for Father’s Day yet? If not, better get to it; Father’s Day is in a week on June 19. Now if you can’t figure out something to buy, the folks over at the New York-based menswear label Ernest Alexander has a solution for all of you who want to get your dad something a little more interesting than the typical brunch and golf options out there: The Dad Box.The Dad Box comes in three options:The Classic Dad Box ($155)Cambridge Rep Stripe Silk NecktieSet of 3 Pocket SquaresMetal Tie BarThe Master Dad Box ($298)Parker Dopp KitOtto Leather Bound Notebook CaseSet of 3 Pocket SquaresHenry Polka Dot Silk NecktieWooden Tie BarSwiss-Made Pocket CombThe Ultimate Dad Box ($498)The Clark Weekender BagParker Dopp KitHenry Polka Dot Silk NecktieWooden Tie BarSwiss-Made Pocket CombNo matter which box you choose, there will surely be something in there that your father will love and cherish forever, like the Parker Dopp Kit, which he could bring with him on all his future travels, or the pocket comb, to make sure every hair is in place, or even the pocket square, so he could look super dapper for his next wedding. So this Father’s Day, give those fathers in your life something that has a little bit of everything: the Ernest Alexander Dad Box. It comes in three tiers, classic, master and ultimate, so whether you want to go all out, or keep it simple, you’ll find something to suit your father’s taste.For more information, visit ernestalexander.com. How to Shave With a Straight Razor The Ultimate Pillow Guide: The 6 Best Pillows for All Sleepers last_img read more

Meyer Werft Announces Float Out of Saga Cruises New Ship

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first_imgzoomSpirit of Discovery in building dock I. Image Courtesy: Meyer Werft Spirit of Discovery, the first of Saga Cruises’ two new cruise ships, will be leaving the covered building dock I at Meyer Werft shipyard in Papenburg, Germany, on May 12, 2019.The float out is scheduled to start at 9:30 am local time, the shipbuilder informed.During the float out, the ship’s mast and funnel will be lifted on the ship. In the evening of the same day, Spirit of Discovery will be moved to the outfitting pier for a number of tests.As disclosed, Ems conveyance is currently planned for the end of May from Papenburg to Emden.Spirit of Discovery is the first of two 58,250 GT newbuilds Meyer Werft is building for the British cruise line. With an overall length of 236 meters, a width of 31.2 meters, each vessel will be able to accommodate 999 passengers.Spirit of Discovery’s sister ship, Spirit of Adventure, is expected to be completed in summer 2020.“The new ships will be tailored to the British market with a completely new design,” Meyer Werft said.last_img read more

Pictou County Lane Closures

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first_imgPICTOU COUNTY: Exit 25 and 27A Exit 25 to New Glasgow to Exit 27A to Sutherlands River on Highway 104, will be reduced to one lane for ashpalt patching from Wednesday, May 7 to Friday, May 9. Some delays expected. Traffic control people are on site. Work takes place from dawn to dusk. -30- Local Are Office: 902-752-6224 Fax: 902-752-7184 last_img

Provincial Government Kicks off United Way Campaign with a Big Splash

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first_img “United Way is delighted and honoured to cheer on these dedicated swimmers, and the many generous provincial employees, volunteers and donors who are passionate about making a difference,” said Sara Napier, president and CEO of United Way Halifax. “This event is creative, ambitious and collaborative. Exactly what we all need to be to improve lives and build strong communities across our province.” Other members of the swim team include: For more than 60 years the provincial government has supported the United Way. Each year, more than 1,600 provincial employees make donations. Contributions help the United Way fund more than 50 agencies and 100 programs across Nova Scotia, ranging from after school programming, literacy, employment training and family resource delivery. “This year’s kickoff has expanded on our successful annual Halifax Harbour swim to create an event that is truly province-wide,” said Mr. Darrow. “We have a great team this year, our biggest yet, and we’re excited to take on the challenge of swimming three harbours in support of such a worthy cause.” A live feed of the Halifax Harbour swim is available at www.novascotia.ca/unitedway/ The CEO of Housing Nova Scotia, Dan McDougall, Halifax-Chebucto MLA Joachim Stroink and a team of swimmers are diving into the challenge of completing not one, not two, but three harbour swims today, Sept. 8 in support of the United Way. The event is kicking off the annual Provincial Government Employees United Way Campaign. This year’s goal is to raise $600,000 for the United Way. “Each year our support gives employees across the province the opportunity to give back to the communities in which we work and live,” said Joanne Munro, CEO of Service Nova Scotia and this year’s United Way campaign lead. “I am honoured to be part of this initiative which plays such a critical role in supporting and helping so many Nova Scotians.” This year’s harbour swim schedule is: 7:15 a.m., Killam’s Marina, 90 Water St., Yarmouth Noon, Bishop’s Landing, 1475 Lower Water St., Halifax 6 p.m., The Fiddle, 74 Esplanade, Sydney Kevin Doran, Communications Nova Scotia Nicholas Phillips, Education and Early Childhood Development Sue LaPierre, United Way, Halifax Troy Bond, Health and Wellness Sean Ward, Justice Denise Blanchard-Carpentier, Labour and Advanced Education Jana Peachey, student Anny Christian, student Dave Darrow, former senior deputy minister last_img read more

Federal ethics watchdog investigates BC Liberal MP after complaint from Tories

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first_imgOTTAWA — The federal ethics watchdog has launched an investigation into allegations that Liberal MP Joe Peschisolido did not disclose that the Law Society of B.C. took control of his law firm earlier this year.Ethics commissioner Mario Dion confirmed in a letter to Conservative MP Peter Kent, who requested the inquiry, that he is looking into the matter.Federal ethics rules require MPs to report any material changes to their investments and other private interests within 60 days.The disclosure summary for the Liberal MP for Steveston-Richmond East still lists him as the sole owner of Peschisolido Law Corporation, even though the provincial law society appointed a custodian to wind up the real estate law practice in April.Kent based his complaint on reporting by Global News, which investigated the role the law firm played in a real estate deal involving an alleged boss of a Chinese drug cartel.Peschisolido says he is “fully co-operating” with the ethics commissioner’s investigation.The Canadian Presslast_img read more

Saks Fifth Avenue opens in Calgary

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first_imgLuxury shoppers have a new destination in Calgary, Saks Fifth Avenue.The new 115 thousand square foot department store officially opens Thursday in the Chinook Centre.The two level space features women’s and men’s items along with luxury handbags, footwear, and accessories.There is also a private jewelry viewing space, beauty treatment rooms, and private shopping suites.A ribbon cutting ceremony at Saks Calgary takes place at 10 a.m.It’s the third Saks Fifth Avenue to open in Canada.last_img read more

King Mohammed VI Congratulates Benchamach on ReElection

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Rabat – King Mohammed VI has congratulated Abdelhakim Benchamach on his re-election as speaker of the House of Councillors at Parliament.The King expressed confidence in Benchamach, owing to his expertise and “strong commitment to the nation’s long-standing and supreme values.”The monarch believes that Benchamach will “redouble his efforts for further action” with all members of the House of Councillors “to consolidate the constructive contribution of this institution.” Read Also: Hakim Benchamach Elected President of House of Councillors for 2nd TermThe King also called on the House of Representatives and the House of Councillors to collaborate to “promote parliamentary action in accordance with the sovereign’s aspirations to see institutions act in the interests of the nation and its citizens, and strengthen the role of the upper house to ensure quality legislation, effective monitoring, relevant public policy assessment and active parliamentary diplomacy.”On Monday, members in the House of Councillors voted in Benchamach as their speaker for a second term.Benchamach won 63 votes; his PJD competitor, Nabil Chikhi, won just 19.Benchamach is the head of the Authenticity and Modernity Party (PAM). He succeeded the former secretary-general of PAM, Ilyas El Omari, in May 2018. read more

Macron visits French farm fair amid rural anger decline

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PARIS — President Emmanuel Macron is visiting France’s biggest agriculture fair amid nationwide anger at government policies seen as favouring urban elites and neglecting the heartland.Macron is trying to tackle the concerns head-on by spending all day Saturday at the Salon d’Agriculture in Paris, where farmers showcase their livestock, food and wines. He will give a speech on upcoming changes to European agricultural policy and then meet with dairy farmers, pork producers, vintners and others.Many French farmers want more government help to face growing foreign competition.Security is tight for Macron’s visit Saturday, which comes as yellow vest protesters plan anti-government protests around Paris and other cities for a 15th straight weekend. Macron was booed at last year’s farm fair over plans to ban a popular pesticide and trade deals.The Associated Press read more

United CEO vows to be aboard 737 Max when its cleared to

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CHICAGO — CEO Oscar Munoz says he will be aboard United Airlines’ first flight of a Boeing 737 Max once regulators agree to let the aircraft fly again.Munoz made the promise after Chicago-based United’s annual meeting with shareholders Wednesday.In crashes in Indonesia in October and Ethiopia in March, an automated system called MCAS mistakenly turned the noses of the planes down in response to faulty readings from a single sensor. Pilots were unable to recover; 346 people died. As a result, regulators grounded the planes.Chicago-based Boeing says it has finished with its updates to the flight-control software implicated in the crashes.Munoz says even after regulatory agencies clear the 737 Max to fly again, it will take more to get passengers comfortable getting on board. He says United in developing a case for the 737 Max, including educating customers and employees about why United feels it’s safe to resume flights.The Associated Press read more

Stocks lower as economic worries weigh on commodities

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The Toronto stock market was lower Friday while commodity prices lost ground on nagging worries about the fragile global economic recovery.The S&P/TSX composite index declined 35.78 points to 11,629.92 while the TSX Venture Exchange was up 2.16 points to 1,193.03.The Canadian dollar lost 0.41 of a cent to 98.82 cents US after the loonie closed at a two-month high on Thursday.Traders also took in data showing Canada’s annual inflation rate rose 0.3 of a percentage point to 1.5 per cent in June, from 1.2 per cent the previous month. On a month-to-month basis, the consumer price index fell 0.4 per cent from May.The increase in the annual rate was mostly attributed to base-effects to June 2010, when gas prices were receding and the cost of new automobiles fell by over three per cent.U.S. markets were lower amid a mixed bag of corporate earnings from heavyweights including Microsoft Corp., General Electric and Xerox.The Dow Jones industrials lost 84.23 points to 12,859.13. The Nasdaq composite index dropped 15.75 points to 2,950.15 and the S&P 500 index declined 8.47 points to 1,368.04.The TSX energy sector was off almost one per cent as oil prices slipped after rising Mideast tensions sent crude up by almost $3 on Thursday.The August crude contract on the New York Mercantile Exchange fell $1.31 to US$91.35 a barrel. Canadian Natural Resources (TSX:CNQ) was down 37 cents to $28.61.Crude rose about five per cent last week as the oil market responded to a series of events that have raised concerns that Iran will try to block oil shipments through the Strait of Hormuz, a narrow waterway in the Persian Gulf through which one-fifth of the world’s oil travels every day.The base metals sector gave back 1.4 per cent with metals also lower with copper down eight cents to US$3.45 a pound. First Quantum Minerals (TSX:FM) gave back 31 cents to $17.97.The tech sector was also a weight while CGI Group (TSX:GIB.A) shed 26 cents to $24.07.The gold sector led advancers, up 0.36 per cent while bullion fell $3.70 to US$1,576.70 an ounce. Barrick Gold Corp. (TSX:ABX) rose 27 cents to $35.35.On the earnings front, General Electric reported Friday that its quarterly net income fell 16 per cent to US$3.11 or 29 cents a share because of losses in businesses it has divested and an increase in pension costs. Excluding pension costs and losses from discontinued businesses, GE earned 38 cents, a penny better than analysts were expecting. It also reaffirmed its outlook.GE also said that it plans to split its energy business into three separate operations. GE is viewed as an important economic bellwether since its businesses range from appliances to financial services to wind and gas turbines. Its stock dipped four cents to US$19.80.Microsoft said Thursday that an accounting adjustment to reflect a weak online ad business led to its first quarterly loss in its 26 years as a public company. Microsoft racked up a $492 million loss in the April-June quarter while revenue rose four per cent to US$18.06 billion. Ex-items, the company earned 73 cents a share, a dime better than forecasts and its shares were up 26.5 cents to US$30.93.But shares in Xerox Corp. cut its full-year profit forecast as the provider of printers and business services said that second-quarter net income fell 3.1 per cent to US$309 million or 22 cents a share, missing forecasts by four cents. Revenue dropped 1.3 per cent to $5.54 billion, against expectations of $5.61 billion. Xerox added that third quarter profits will also miss estimates. Xerox shares dropped 13.5 cents to US$7.055.The TSX appeared heading for an overall gain for this week on rising expectations that central banks will step up to ensure the economic recovery stays on the rails.Earlier this week, Federal Reserve chairman Ben Bernanke appeared before Congressional panels and while he did not indicate that another round of stimulus was imminent, his comments led investors to believe further action remained an option. The Fed has already completed two programs of asset purchases, which have the effect of increasing the supply of money.Other central banks have embarked on more stimulus in recent weeks by cutting rates, including those in South Korea, the European Union, and China. There was another reminder Friday how China, the world’s second biggest economy, is slowing as a result of government efforts to choke off high inflation.The government says total profit for its biggest state-owned companies is down sharply. The state Xinhua News Agency said Friday the agency that oversees the top 117 state companies reported first-half profit was down 16.4 per cent from a year earlier. It gave no details of individual companies.China’s economic growth slowed to a three-year low of 7.6 per cent in the second quarter. Analysts say the decline probably has bottomed out but they say the strength of a recovery is uncertain.The risk-on sentiment grew as the yield on Spain’s benchmark 10-year bond ran up to 7.05 per cent on Friday, from 6.98 per cent the previous day. A rate of seven per cent and above is widely considered too expensive for the Spanish government to pay for more than a few months.Yields rose even as finance ministers from the 17 euro countries approved a bailout for Spanish banks. But investors fear that the Spanish government could in the meantime face new costs helping its banks and could eventually need rescue loans itself.European indexes were solidly in the red as London’s FTSE 100 index lost 0.72 per cent, Frankfurt’s DAX dropped 0.97 per cent while the Paris CAC 40 lost 1.63 per cent. read more

ICE Futures Canada Friday morning Canola prices mixed barley unchanged

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WINNIPEG — Prices were mixed in mid-morning trading at ICE Futures Canada on Friday:Canola: Nov. ’17 $2.00 lower $508.20; Jan. ’18 $2.30 lower $512.60; March ’18 $1.90 lower $516.00; May ’18 $0.30 higher $518.30; July ’18 $1.50 higher $520.80; Nov. ’18 $1.90 higher $487.50; Jan. ’19 unchanged $486.40; March ’19 unchanged $489.10; May ’19 unchanged $489.10; July ’19 unchanged $489.10.Barley (Western): Oct. ’17 unchanged $140.00; Dec. ’17 unchanged $140.00; March ’18 unchanged $140.00; May ’18 unchanged $140.00; July ’18 unchanged $140.00; Oct. ’18 unchanged $140.00; Dec. ’18 unchanged $140.00; March ’19 unchanged $140.00; May ’19 unchanged $140.00; July ’19 unchanged $140.00. read more

Ramith Rambukwellas driving licence suspended

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The driving licence of former Minister Keheliya Rambukwella’s son Ramith Rambukwella’s was suspended by the Traffic Court today.Rambukwella was arrested recently over an accident which took place at Independence Avenue in Colombo while he was under the influence of alcohol. Rambukwella was released on police bail. Ramith Rambukwella is also a member of the Sri Lanka cricket team. (Colombo Gazette)

US control board to probe Puerto Rico debt ties to crisis

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US control board to probe Puerto Rico debt, ties to crisis by Danica Coto, The Associated Press Posted Aug 2, 2017 3:31 pm MDT Last Updated Aug 2, 2017 at 5:00 pm MDT AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email SAN JUAN, Puerto Rico – A federal control board overseeing the finances of Puerto Rico’s government said Wednesday that it will investigate the causes of the island’s economic crisis as well as examine how its debt was issued and probe disclosure and selling practices.The announcement comes as government officials seek to restructure a portion of the $70 billion public debt in a process similar to bankruptcy following multimillion-dollar defaults that have angered creditors.Board members said they will form a special committee that will appoint an independent investigator, and the findings will be made public. The board said the investigation aims to restore fiscal balance and help Puerto Rico re-enter the capital market.It is unclear what happens next if significant findings emerge and whether any federal government agencies would become involved. The board did not respond to a request for additional comment.Puerto Ricans affected by austerity measures amid a 10-year recession and those who have faced big losses after investing in government bonds have long demanded an audit of the debt as they seek to hold officials accountable. A federal judge next week is expected to address a demand by a group of creditors to probe what role several banks played in the sale of debt obligations.Economist Vicente Feliciano said the investigation adds uncertainty to debt restructurings hearings that recently began in federal court.“At the same time, it strengthens the position of the board and the government when negotiating with creditors,” he said, adding that creditors may be willing to make additional concessions before the investigation concludes.One fear creditors may have is that the investigator finds some of the debt may have been illegally issued, which raises the question of whether it should be paid, he said.Records show that the U.S. Securities and Exchange Commission also has been investigating Puerto Rico bond sales. read more

Mark Sanchez Placed on Jets Injured Reserve

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Mark Sanchez was placed on short-term injured reserve Saturday, the New York Jets announced.Placed on IR, by rule, the quarterback must miss six weeks of practice and eight games.Head coach Rex Ryan said earlier in the week that it was “realistic” for Sanchez to play again this season. Team doctors advised Sanchez that surgery is not necessary at this time, and that he could rehabilitate the shoulder.The QB tore the labrum in his throwing shoulder after he was drilled by New York Giants defensive tackle Marvin Austin. The injury happened while Sanchez was going through an intense summer-long competition with rookie Geno Smith for the starting quarterback spot.General manager John Idzik said in a statement on Sept. 4 that “we’re not looking at (injured reserve). We’re looking at Mark continuing to rehab. He’s day to day.”Sanchez told the NFL Network Thursday that he would try his best to play again this season. read more

Marine and his mother convicted of murdering grandmother after police catch him

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first_imgPenelope John leaves Swansea Crown Court last month A marine and his mother have been convicted of murdering his grandmother after police caught him admitting the crime by bugging his house.Iraq veteran Barry Rogers used a pillow to smother Betty Guy, 84, after his mother Penelope John had given her a cocktail of pills and whisky on November 7 2011.Mrs Guy’s death was initially thought to be from natural causes and no post-mortem examination was carried out.However, Rogers, 33, and John, 50, came under suspicion four years later when an ex-partner of Rogers told police he said he had killed his grandmother by putting a pillow over her face.Officers also found two other previous partners of Rogers who said he had told them about his part in Mrs Guy’s death.John, of St Dogmaels, Pembrokeshire, and Rogers of Fishguard, Pembrokeshire, were arrested on October 6 2016 and while they were in custody officers installed covert recording equipment in John’s home. Penelope John leaves Swansea Crown Court last monthCredit:Dimitris Legakis/Athena Pictures The jury heard recordings where the pair discussed Mrs Guy’s death in terms which were “inconsistent with her having died naturally and peacefully”. At one point Rogers could be heard saying to his mother: “You have got nothing to worry about, it’s me that’s the one that’s done the act.”After the case finished yesterday, with sentencing adjourned, another of Mrs Guy’s children, Lorraine Matthews said justice had prevailed. The home where Betty Guy was murdered in Haverfordwest, Wales The home where Betty Guy was murdered in Haverfordwest, WalesCredit:Martin Cavaney/Athena Picturescenter_img The pair denied murder but were convicted by a jury of five women and seven men following a trial at Swansea Crown Court.The judge in the case, Mr Justice Lewis said both Rogers and John would receive life sentences of imprisonment.He said he would look at the authorities on mercy killings in preparations, despite both defendants having denied killing Mrs Guy for any reason, including a mercy killing.He said: “You have been found guilty of the murder of Betty Guy. I order that both of you be remanded in custody. “I direct that you be brought back to court on Thursday February 8 whereupon I will sentence you to the sentence required by the law which is life imprisonment and the appropriate minimum term.”Rogers and John were remanded in custody to appear before the court for sentence on Thursday. Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily  Front Page newsletter and new  audio briefings. “Seven years after my mother’s death, my brothers, my sons, myself and other members of the family, were shocked and horrified to learn from the police that my mother, Mrs Betty Guy, may not have died from natural causes and that my sister and her son were to be charged with her murder,” she said in a statement released by Dyfed-Powys Police.”Over the past three years the police have worked tirelessly to collect sufficient evidence to bring this case to court.”Now that the case has drawn to a close we are satisfied that justice has prevailed and now we can close this very sad chapter in our lives.”last_img read more