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Can psychedelic drugs be used in the treatment of mental illness?

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first_imgPsychedelic drugs such as LSD (lysergic acid diethylamide), psilocybin and ketamine have been rediscovered by researchers in neuroscience and psychiatry. A recent review in the Journal of Psychopharmacology highlights the distinct therapeutic effects of psychedelics, as well as the current re-evaluation of their use in the treatment of addiction, anxiety in terminally ill patients, depression, cluster headaches and obsessive-compulsive disorder (OCD).A psychedelic drug is a psychoactive drug whose primary action is to alter cognition and perception. Since the discovery of LSD in 1943, psychedelic drugs have been of major scientific interest. Despite clinical psychedelic research coming to a standstill in the mid-1970s (due to regulatory restrictions), an increase in methodological quality standards, neurobiological method and neuroimaging, as well as interest in the interest of the neurosciences in subjective experience, has meant a re-emergence of interest.The review by Tomislav Majić (Charité University Medicine, Berlin), Timo Schmidt (Free University Berlin) and Jürgen Gallinat  (University Medical Center Hamburg-Eppendorf), looked at current clinical research and re-evaluated former and recent concepts of where and how psychedelic substances exert their therapeutic effects. Share on Twitter Share on Facebook Email Pinterestcenter_img LinkedIn Share Key findings included that ketamine is effective in the treatment of substance addiction, both through the psychedelic experiences and it’s enhancing of personal meaning and spiritual significance. Ketamine has also been used to produce short-term anti-depressive effects in major depression and bipolar disorder, through its altering of perception (It has also been proposed as a treatment option for affective disorders based on its pharmacological effects).LSD has been shown to be beneficial in the treatment of alcohol abuse when used in combination with therapy.Psilocybin, the main component of so-called magic mushrooms, has been recently shown to be effective in the treatment of anxiety in cancer patients, not by reducing pain, but by inducing feelings of strengthened rapport and relationships with close relatives and friends. Recent research has also highlighted the therapeutic use of LSD and psilocybin in treating cluster headaches. Interestingly, it was reported that the therapeutic effects appear to be completely independent of the psychedelic experience.The review reported converging evidence suggesting that serotonergic neurotransmission plays a key role in the mechanism of these psychedelic drugs – the neurotransmitter serotonin is thought to play an important role in the brain relating to mood, anxiety and happiness.The findings of the review concluded that psychedelic drugs are unique in the sense that they: have neurochemical and pharmacodynamics effects (e.g. in the treatment of depression and possibly OCD); support various types of psychotherapy (e.g. in the treatment of terminal illness); can be used to treat headaches or other pain syndromes; and they often result in spiritual experiences through which they can assist in therapy (e.g. in the treatment of substance addiction). Furthermore, in contrast to traditional psychiatric drugs, they are only to be taken once or a few times.The review highlights the potential for psychedelic drugs to be used in clinical settings, although more research is required to develop a deeper understanding of their therapeutic effects and how they work.last_img read more

Mengacu Data Intelijen, AS dan Kanada Yakin Boeing 737 Ukraine International…,Terdeteksi Mabuk, Pramugari ANA Tunda Empat Penerbangan Secara Beruntun

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first_imgPuing-puing dari Boeing 737-800 Ukraine International Airlines usai dirudal Iran. Foto: Business Insider Dugaan ditembak jatuhnya pesawat Ukraine International Airlines semakin menguat manakala Perdana Menteri Kanada, Justin Trudeau mengatakan bahwa bisa saja penembakan rudal tersebut tidak disengaja. Ujaran Justin ini didukung oleh laporan intelijen Kanada yang ia terima. Ya, pada Rabu (8/1) kemarin, pesawat Boeing 737-800 milik Ukraine International Airlines jatuh di Teheran, Iran tak lama berselang setelah pesawat tinggal landas. Pada insiden ini, sebanyak 176 orang yang ada di dalam pesawat dinyatakan meninggal – dimana 63 diantaranya adalah warga negara Kanada.Baca Juga: Inilah Lima Spekulasi Jatuhnya Boeing 737-800 Ukraine International di Iran“Kami memiliki data dari berbagai sumber, termasuk dari sekutu dan intelijen kami sendiri. Data tersebut menunjukkan bahwa pesawat ditembak jatuh oleh rudal darat milik Iran,” ujar Justin, dilansir KabarPenumpang.com dari laman Reuters.com (9/1). Seolah mendukung pernyataan dari Justin, sebanyak tiga pejabat Amerika Serikat juga mengatakan bahwa Pemerintah Negeri Paman Sam percaya bahwa pihak Iran telah secara tidak sengaja menembak jatuh pesawat Ukraine International Airlines.Ditambah lagi dengan pernyataan Presiden Amerika Serikat, Donald Trump yang mengatakan bahwa dirinya tidak percaya bahwa pesawat Ukraine International Airlines jatuh karena masalah teknis.“Itu (insiden jatuhnya pesawat) adalah hal yang tragis. Tetapi seseorang bisa saja membuat kesalahan,” ujar Presiden Trump di hadapan wartawan di Gedung Putih.Justin juga mengatakan bahwa pihaknya tidak akan ‘beristirahat’ hingga mereka mendapatkan kejelasan, transparansi, akuntabilitas, dan keadilan dari insiden ini. Pada Kamis (9/1), seorang pejabat di Pemerintahan Amerika Serikat mengutip tinjauan luas terhadap data satelit dan pihak Washington menyimpulkan dengan sangat yakin bahwa pesawat Ukraine International jatuh akibat tembakan rudal – salah satu data yang dijadikan acuan adalah terdeteksinya heat signature dari dua rudal darat yang muncul tak lama berselang setelah pesawat tinggal landas.Baca Juga: Di Tengah Ketegangan Iran-AS, Boeing 737-800 Ukraine International Jatuh di IranKetika dikonfirmasi ke pihak Iran, juru bicara pemerintahan, Ali Rabiei menampik segala hipotesa yang beredar luas di publik – terutama yang menyudutkan pihak Iran.Namun jika pada akhirnya terbukti bahwa pesawat Ukraine International Airlines jatuh karena rudal darat milik Iran, berarti besar kemungkinan bahwa ini merupakan dampak dari meningkatnya ketegangan militer dengan Amerika Serikat. Sebagai informasi, pesawat nahas ini terbang beberapa saat setelah Iran melancarkan serangan rudal balistik ke basis militer AS di Irak.Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading… Relatedlast_img read more

FC Bayern Munich reportedly scrapping esports plans

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first_imgAt one point it seemed as if German football club FC Bayern Munich was poised to enter the esports industry, but a new report suggests those plans have been scrapped.According to German tabloid Bild.de, FC Bayern Munich’s president Ulrich “Uli” Hoeness has decided against the advanced plans to enter multiple esports titles.At one point, the football club wanted to invest as much as €5,000,000 (£4,397,899) into entering games such as League of Legends, Dota 2, and Fortnite. Nonetheless, Hoeness has vetoed these plans since he sees no correlation between esports and his team.Said talks around this entrance into esports have been present for two years, at least, when Bundesliga sides VfL Wolsburg and FC Schalke 04 made their mark in the industry. Despite these now-scrapped plans, Bayern’s basketball counterpart had fielded an NBA 2K roster under the guise of Bayern Ballers.This news has not been confirmed as of yet, it has merely been reported so it should be taken with a pinch of salt. It’s worth noting that it costs a lot more than the proposed investment to enter League of Legends alone should FC Bayern Munich have wanted to acquire a spot in the upcoming franchised-take on the EU LCS.Esports Insider says: We can’t help but think this is a huge missed opportunity and a misstep from the German side should this report turn out to be truthful. With teams such as FC Barcelona recently entering the scene, and existing clubs still operating in multiple titles, it’d be a shame to see a club that’s the size of FC Bayern Munich deciding against entering esports.Sign up to our newsletter!last_img read more

Fergie bags managers’ award

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first_img0Shares0000LONDON, England, May 21 – Outgoing Manchester United manager Alex Ferguson heads into retirement with the Premier League manager of the year award.Ferguson picked up the League Manager Association’s honour on Monday. At the reception the 71-year-old said he was relieved celebrations to mark his retirement were over.“It has been overwhelming,” he told the awards dinner in London 24 hours after his last match in charge of United, Sunday’s 5-5 draw at West Brom.“The club has been fantastic and congratulations to West Brom with the way they handled yesterday.In a way I am glad it is all over now – because it has been a very hard week.“I think (West Brom manager) Steve Clarke should get an award because anyone who scores five against United deserves it.”0Shares0000(Visited 1 times, 1 visits today)last_img read more

Presidents science adviser attacks COMPETES bill in US House raises concern about

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first_imgThe COMPETES bill has been widely assailed by the U.S. scientific community since a truncated version first appeared 2 years ago. The panel’s chair, Representative Lamar Smith (R–TX), has said he took that criticism to heart in drafting the current bill, which is meant to succeed a 2007 law, extended in 2010, that expired in 2013.Holdren indirectly acknowledged some of those changes in his comments. But he made it clear that he thinks the bill, which would significantly reduce authorized funding levels for the social and earth sciences at the National Science Foundation (NSF) and make changes in NSF’s grantsmaking process, is still seriously flawed.“The introductory language is great, but the contents are less great,” Holdren explained. “The bill singles out for quite aggressive cuts at NSF’s social and behavioral sciences. Some in Congress appear to believe that social and behavioral science is not really science, despite the 1950 organic act makes clear that progress in all fields of science, including the social and behavioral sciences, is the foundation’s mission.”“The bill also makes quite substantial cuts in the earth sciences. There are some in Congress who question whether earth science is really science,” he said. “I find that quite bizarre.”Challenges at NASAHoldren was more restrained in discussing the NASA reauthorization, which the panel began marking up at 11 a.m., barely 1 hour after Holdren ended his talk. At 1:36 p.m., the committee passed the bill (H.R. 2039) on a straight party-line vote of 19 to 15.“Another challenge is to how reconcile the administration and congressional priorities for NASA,” Holdren noted. “I’ve long said that the big problem with NASA is that it is trying to fit 20 pounds of missions into a 10-pound budget. NASA has an enormously diverse array of responsibilities … and its $18 billion budget, which may seem large, has never been enough to do what is desirable in all those domains.” But Holdren said the proposed legislation’s proposed large cut in authorized funding levels for the agency’s earth sciences program “is not the direction we need to be going.”Speaking to ScienceInsider after his talk, Holdren said that he would welcome a chance to talk with Republican legislators about making changes in the bill. “My hope is that we’ll find room for compromise. But it’s going to take a lot of work.” He declined to say whether he would prefer to see no bill enacted rather than the current legislation, but acknowledged that “there are good things that would be lost” if the bills were not adopted.*Clarification, 30 April, 2:50 p.m.: This story has been updated to clarify that today was the first time the White House commented on the COMPETES bill. Email Sign up for our daily newsletter Get more great content like this delivered right to you! Country Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwecenter_img The president’s science adviser today criticized science policy legislation moving through the U.S. House of Representatives, hinting that his boss would veto the two bills if they ever reached his desk.Speaking at the annual Forum on Science and Technology Policy sponsored by AAAS (publisher of ScienceInsider), John Holdren had harsh words for the America COMPETES Act approved last week by the House science committee. He also expressed concern about a bill being marked up today by the science committee to reauthorize NASA programs. It’s the first comment on either bill by the White House, which typically refrains from taking an official position on legislation until it is scheduled for a vote by the full House or Senate.“In my personal opinion, the COMPETES bill as it now stands is bad for science, it’s bad for scientists and engineers, bad for the federal science agencies, and damaging to the world-leading U.S. scientific enterprise,” Holdren told the Washington, D.C., audience. Click to view the privacy policy. Required fields are indicated by an asterisk (*)last_img read more