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Can psychedelic drugs be used in the treatment of mental illness?

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first_imgPsychedelic drugs such as LSD (lysergic acid diethylamide), psilocybin and ketamine have been rediscovered by researchers in neuroscience and psychiatry. A recent review in the Journal of Psychopharmacology highlights the distinct therapeutic effects of psychedelics, as well as the current re-evaluation of their use in the treatment of addiction, anxiety in terminally ill patients, depression, cluster headaches and obsessive-compulsive disorder (OCD).A psychedelic drug is a psychoactive drug whose primary action is to alter cognition and perception. Since the discovery of LSD in 1943, psychedelic drugs have been of major scientific interest. Despite clinical psychedelic research coming to a standstill in the mid-1970s (due to regulatory restrictions), an increase in methodological quality standards, neurobiological method and neuroimaging, as well as interest in the interest of the neurosciences in subjective experience, has meant a re-emergence of interest.The review by Tomislav Majić (Charité University Medicine, Berlin), Timo Schmidt (Free University Berlin) and Jürgen Gallinat  (University Medical Center Hamburg-Eppendorf), looked at current clinical research and re-evaluated former and recent concepts of where and how psychedelic substances exert their therapeutic effects. Share on Twitter Share on Facebook Email Pinterestcenter_img LinkedIn Share Key findings included that ketamine is effective in the treatment of substance addiction, both through the psychedelic experiences and it’s enhancing of personal meaning and spiritual significance. Ketamine has also been used to produce short-term anti-depressive effects in major depression and bipolar disorder, through its altering of perception (It has also been proposed as a treatment option for affective disorders based on its pharmacological effects).LSD has been shown to be beneficial in the treatment of alcohol abuse when used in combination with therapy.Psilocybin, the main component of so-called magic mushrooms, has been recently shown to be effective in the treatment of anxiety in cancer patients, not by reducing pain, but by inducing feelings of strengthened rapport and relationships with close relatives and friends. Recent research has also highlighted the therapeutic use of LSD and psilocybin in treating cluster headaches. Interestingly, it was reported that the therapeutic effects appear to be completely independent of the psychedelic experience.The review reported converging evidence suggesting that serotonergic neurotransmission plays a key role in the mechanism of these psychedelic drugs – the neurotransmitter serotonin is thought to play an important role in the brain relating to mood, anxiety and happiness.The findings of the review concluded that psychedelic drugs are unique in the sense that they: have neurochemical and pharmacodynamics effects (e.g. in the treatment of depression and possibly OCD); support various types of psychotherapy (e.g. in the treatment of terminal illness); can be used to treat headaches or other pain syndromes; and they often result in spiritual experiences through which they can assist in therapy (e.g. in the treatment of substance addiction). Furthermore, in contrast to traditional psychiatric drugs, they are only to be taken once or a few times.The review highlights the potential for psychedelic drugs to be used in clinical settings, although more research is required to develop a deeper understanding of their therapeutic effects and how they work.last_img read more

The Hershey Bears win fifth straight game, beat Hartford 2-3

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first_imgThe Hershey Bears won their fifth straight game of the season Friday night against the Harford Wolfpack. It would take almost twenty five minutes for anyone to score as Nathan Walker put Hershey on the board at 4:31 with a quick pass from Jeremy Langlois.  However with less than two minutes left in the middle period Cole Schneider would tie the game.The rest of the game would play out, scoreless until former Hartford Wolfpack, Joe Whitney would score on the faceoff at 17:57 i, making the score 2-1. This would be Whitney’s first time playing in Hartford since being traded to Hershey on February ninth of this year.With Hartford’s goalie Chris Nell on the bench, Hartfod gained a 6-on-5 advantage and Scott Kosmachuk would capitalize scoring a game tying goal bringing the score to 2-2 at 18:23. As fans prepared for what looked like overtime in the making, Hershey would answer back with a quick pass from Tyler Graovac, and Nathan Walker would score the game winning goal less than 10 seconds later at 18:32. Jeremy Langlois would add an empty net goal just over a minute later at 19:33 and Hershey would add a tally to the final score, making it 4-2.The fifth straight win for The Hershey Bears is the longest winning streak of the season and brings their record to 23-25-3-4. Hershey outshot Hartford 29-23.Hershey will host the Rockford IceHogs Saturday night at Hershey Giant Center, game starts at 7pm. Hershey will be headed up north to Wilkes-Barre/ Scranton to take on the Baby Pens with a 3pm early start!Please follow and like us:last_img read more

MS Dhoni cheated of over Rs 20 crore by Spartan Sports

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first_imgIndia’s limited-overs captain MS Dhoni is one of the most marketable athletes in the world and has many multi-million dollar deals to his name. So it is probably not a good idea to mess with him, which is exactly what Australian sports brand Spartan Sports has done.Dhoni, who endorses many top brands, has been cheated of over Rs 20 crore by the sports manufacturing giant. It has been reliably learnt that a three-year bat and sponsorship deal worth Rs 13 crore has gone sour with Spartan Sports, a sporting gear and equipment company, regularly defaulting on payments. With the royalty clause on Dhoni’s bat deal included, the owed amount reportedly goes well over Rs 20 crore.Sources in legal firm advising Rhiti Sports, Dhoni’s management company, told PTI that Kunal Sharma-owned Spartan has paid only four installments since the deal was struck in December 2013, the latest payment being made in March 2016.When asked why the deal has gone awry, Rhiti Sports boss Arun Pandey did not elaborate before saying that, “everything is not smooth and hopefully the matter will be resolved soon”.Besides Dhoni, the Australian company interestingly has big names of the cricketing world as its ambassadors – former Australian captain Michael Clarke, West Indies batsman Chris Gayle, England cricketer Eoin Morgan, former Australian pacer Mitchell Johnson and Sir Viv Richards to name a few.(With PTI inputs)last_img read more