Can psychedelic drugs be used in the treatment of mental illness?

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first_imgPsychedelic drugs such as LSD (lysergic acid diethylamide), psilocybin and ketamine have been rediscovered by researchers in neuroscience and psychiatry. A recent review in the Journal of Psychopharmacology highlights the distinct therapeutic effects of psychedelics, as well as the current re-evaluation of their use in the treatment of addiction, anxiety in terminally ill patients, depression, cluster headaches and obsessive-compulsive disorder (OCD).A psychedelic drug is a psychoactive drug whose primary action is to alter cognition and perception. Since the discovery of LSD in 1943, psychedelic drugs have been of major scientific interest. Despite clinical psychedelic research coming to a standstill in the mid-1970s (due to regulatory restrictions), an increase in methodological quality standards, neurobiological method and neuroimaging, as well as interest in the interest of the neurosciences in subjective experience, has meant a re-emergence of interest.The review by Tomislav Majić (Charité University Medicine, Berlin), Timo Schmidt (Free University Berlin) and Jürgen Gallinat  (University Medical Center Hamburg-Eppendorf), looked at current clinical research and re-evaluated former and recent concepts of where and how psychedelic substances exert their therapeutic effects. Share on Twitter Share on Facebook Email Pinterestcenter_img LinkedIn Share Key findings included that ketamine is effective in the treatment of substance addiction, both through the psychedelic experiences and it’s enhancing of personal meaning and spiritual significance. Ketamine has also been used to produce short-term anti-depressive effects in major depression and bipolar disorder, through its altering of perception (It has also been proposed as a treatment option for affective disorders based on its pharmacological effects).LSD has been shown to be beneficial in the treatment of alcohol abuse when used in combination with therapy.Psilocybin, the main component of so-called magic mushrooms, has been recently shown to be effective in the treatment of anxiety in cancer patients, not by reducing pain, but by inducing feelings of strengthened rapport and relationships with close relatives and friends. Recent research has also highlighted the therapeutic use of LSD and psilocybin in treating cluster headaches. Interestingly, it was reported that the therapeutic effects appear to be completely independent of the psychedelic experience.The review reported converging evidence suggesting that serotonergic neurotransmission plays a key role in the mechanism of these psychedelic drugs – the neurotransmitter serotonin is thought to play an important role in the brain relating to mood, anxiety and happiness.The findings of the review concluded that psychedelic drugs are unique in the sense that they: have neurochemical and pharmacodynamics effects (e.g. in the treatment of depression and possibly OCD); support various types of psychotherapy (e.g. in the treatment of terminal illness); can be used to treat headaches or other pain syndromes; and they often result in spiritual experiences through which they can assist in therapy (e.g. in the treatment of substance addiction). Furthermore, in contrast to traditional psychiatric drugs, they are only to be taken once or a few times.The review highlights the potential for psychedelic drugs to be used in clinical settings, although more research is required to develop a deeper understanding of their therapeutic effects and how they work.last_img read more

Player open to making Leicester City permanent exit, already told club…

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first_imgThe reports have been coming from the English and Turkish press, and the Lisbon outlet sounds excited about it, as they give the story a big article in today’s edition.Now A Bola doesn’t have much to add about the negotiations, but are sure about one thing: Slimani would be really keen about returning to Sporting.They say the player has been open to this move for a long time now, and already told Sporting he would happy to be a Lion again.Embed from Getty ImagesSlimani has only five goals in 25 appearances for Fenerbahce this season, and his return to Leicester City in the summer sounds very likely.Things haven’t worked out well for him since joining the Foxes on a €30m deal in 2016.As he’s considered to be an ‘expensive’ player by the Portuguese clubs, a move back to Lisbon would only happen if Leicester present good conditions for it.by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksTrending TodayForge of Empires – Free Online GameChallenge Your Brain With This Must-Play Strategy Game. No Install.Forge of Empires – Free Online GameUndoRaid: Shadow Legends | Free DownloadEven Non-Gamers Are Obsessed With This RPG Game (It’s Worth Installing!)Raid: Shadow Legends | Free DownloadUndoDating.comWhere do attractive singles find each other in Tung Chung?Dating.comUndoPerfect-Dating.comReveal Tung Chung As The Best City to Date for Love & RomancePerfect-Dating.comUndoKeto减肥1個簡單的妙招一夜「融化」腹部贅肉(今晚試試)Keto减肥UndoCNBC InternationalHere’s How Big Businesses in Singapore Are Managing the Impact of COVID-19.CNBC InternationalUndo熱門話題小心會長過頭…網友推爆:「真的長得超誇張!」熱門話題UndoSingles50Hong Kong: A 40+ Dating Site That Actually Works!Singles50UndoCoworking Space | Search AdsThe cost of shared office in Hong Kong might surprise youCoworking Space | Search AdsUndo Portuguese newspaper A Bola highlights today the recent claims which said Leicester City striker Islam Slimani could soon return to Sporting.last_img read more

Were PSLs really an ‘investment’ all those years ago? Ravens fans will soon find out

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first_imgPart 3: The Ghost of Baltimore Football FutureAs Baltimore Ravens president Dick Cass recently pointed out in a letter to the club’s Personal Seat License holders and top financial supporters, the spaciousness of the team’s home games this season can certainly be traced back to a warm afternoon a continent away in London, England when a dozen players took The Wembley Knee during the National Anthem.Or, on “foreign soil,” as so many patriots have stated on the internet. It’s unclear how many PSL owners are purposely keeping those seats empty as a boycott and how many just can’t resell or even give away the tickets for free as a gift.The new “cool debate” during the holidays has been the loyal Ravens fans excited about a playoff berth and still going to the games fighting with the ones who used to go to the games about how any real, true-blooded American could possibly support the National Football League and these disrespectful black players who hate our military and The President.That’s where we are in this debate entering 2018.But you want me to “stick to sports,” right?Let’s be clear about how the upper deck got empty and how the fan base got uppity: if Donald J. Trump didn’t go on the attack with NFL players and call them “sons of bitches,” The Wembley Knee wouldn’t exist nor would The Knee of 180 players of color that around the sport that day in September 2017.No sane person should argue this point.But, no matter the reason, rationale, politics, philosophy, patriotism or the color of your skin or theirs, the result has been quite eye-opening for anyone who has witnessed a home game for the Baltimore Ravens since The Wembley Knee and subsequent drubbing at the hands of the Jacksonville Jaguars in London back on September 24th.Time will tell what the impact of The Wembley Knee will be in the coming years to season tickets and PSLs and their street value.Time will also tell what real damage there will be to the franchise and how it rebounds from this political crisis that Steve Bisciotti never could’velast_img read more